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The route to transcription initiation determines the mode of transcriptional bursting in E. coli
Transcription is fundamentally noisy, leading to significant heterogeneity across bacterial populations. Noise is often attributed to burstiness, but the underlying mechanisms and their dependence on the mode of promotor regulation remain unclear. Here, we measure E. coli single cell mRNA levels for...
Autores principales: | Engl, Christoph, Jovanovic, Goran, Brackston, Rowan D., Kotta-Loizou, Ioly, Buck, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229158/ https://www.ncbi.nlm.nih.gov/pubmed/32415118 http://dx.doi.org/10.1038/s41467-020-16367-6 |
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