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Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

Cell replacement is a long-standing and realistic goal for the treatment of Parkinsonʼs disease (PD). Cells for transplantation can be obtained from fetal brain tissue or from stem cells. However, after transplantation, dopamine (DA) neurons are seen to be a minor component of grafts, and it has rem...

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Detalles Bibliográficos
Autores principales: Tiklová, Katarína, Nolbrant, Sara, Fiorenzano, Alessandro, Björklund, Åsa K., Sharma, Yogita, Heuer, Andreas, Gillberg, Linda, Hoban, Deirdre B., Cardoso, Tiago, Adler, Andrew F., Birtele, Marcella, Lundén-Miguel, Hilda, Volakakis, Nikolaos, Kirkeby, Agnete, Perlmann, Thomas, Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229159/
https://www.ncbi.nlm.nih.gov/pubmed/32415072
http://dx.doi.org/10.1038/s41467-020-16225-5