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Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease
Cell replacement is a long-standing and realistic goal for the treatment of Parkinsonʼs disease (PD). Cells for transplantation can be obtained from fetal brain tissue or from stem cells. However, after transplantation, dopamine (DA) neurons are seen to be a minor component of grafts, and it has rem...
Autores principales: | Tiklová, Katarína, Nolbrant, Sara, Fiorenzano, Alessandro, Björklund, Åsa K., Sharma, Yogita, Heuer, Andreas, Gillberg, Linda, Hoban, Deirdre B., Cardoso, Tiago, Adler, Andrew F., Birtele, Marcella, Lundén-Miguel, Hilda, Volakakis, Nikolaos, Kirkeby, Agnete, Perlmann, Thomas, Parmar, Malin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229159/ https://www.ncbi.nlm.nih.gov/pubmed/32415072 http://dx.doi.org/10.1038/s41467-020-16225-5 |
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