Cargando…

BIG1 controls macrophage pro-inflammatory responses through ARF3-mediated PI(4,5)P2 synthesis

Sepsis is caused by a dysregulated host inflammatory response to serious infections resulting in life-threatening organ dysfunction. The high morbidity and mortality make sepsis still a major clinical problem. Here, we investigated the roles of Brefeldin A-inhibited guanine nucleotide-exchange facto...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Lixin, Zhang, Sulin, Wang, Yirui, Bao, Weilian, Zhou, Yile, Dang, Wenzhen, Wang, Xu, Li, Haidong, Cao, Xinyue, You, Yan, Fang, Hao, Shen, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229175/
https://www.ncbi.nlm.nih.gov/pubmed/32415087
http://dx.doi.org/10.1038/s41419-020-2590-1