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The native ORAI channel trio underlies the diversity of Ca(2+) signaling events

The essential role of ORAI1 channels in receptor-evoked Ca(2+) signaling is well understood, yet little is known about the physiological activation of the ORAI channel trio natively expressed in all cells. The roles of ORAI2 and ORAI3 have remained obscure. We show that ORAI2 and ORAI3 channels play...

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Detalles Bibliográficos
Autores principales: Yoast, Ryan E., Emrich, Scott M., Zhang, Xuexin, Xin, Ping, Johnson, Martin T., Fike, Adam J., Walter, Vonn, Hempel, Nadine, Yule, David I., Sneyd, James, Gill, Donald L., Trebak, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229178/
https://www.ncbi.nlm.nih.gov/pubmed/32415068
http://dx.doi.org/10.1038/s41467-020-16232-6