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Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine

Despite the abundance of ribonucleoside monophosphates (rNMPs) in DNA, sites of rNMP incorporation remain poorly characterized. Here, by using ribose-seq and Ribose-Map techniques, we built and analyzed high-throughput sequencing libraries of rNMPs derived from mitochondrial and nuclear DNA of buddi...

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Detalles Bibliográficos
Autores principales: Balachander, Sathya, Gombolay, Alli L., Yang, Taehwan, Xu, Penghao, Newnam, Gary, Keskin, Havva, El-Sayed, Waleed M. M., Bryksin, Anton V., Tao, Sijia, Bowen, Nicole E., Schinazi, Raymond F., Kim, Baek, Koh, Kyung Duk, Vannberg, Fredrik O., Storici, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229183/
https://www.ncbi.nlm.nih.gov/pubmed/32415081
http://dx.doi.org/10.1038/s41467-020-16152-5