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The science of puromycin: From studies of ribosome function to applications in biotechnology
Puromycin is a naturally occurring aminonucleoside antibiotic that inhibits protein synthesis by ribosome-catalyzed incorporation into the C-terminus of elongating nascent chains, blocking further extension and resulting in premature termination of translation. It is most commonly known as a selecti...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Research Network of Computational and Structural Biotechnology
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229235/ https://www.ncbi.nlm.nih.gov/pubmed/32435426 http://dx.doi.org/10.1016/j.csbj.2020.04.014 |