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Systemic TNF-α blockade attenuates anxiety and depressive-like behaviors in db/db mice through downregulation of inflammatory signaling in peripheral immune cells

Research studies have indicated that the comorbidity burden of mood disorders and obesity is reasonably high. Insulin signaling has been shown to modulate multiple physiological functions in the brain, indicating its association with neuropsychiatric diseases, including mood disorders. Leptin is a h...

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Detalles Bibliográficos
Autores principales: Alshammari, Musaad A., Khan, Mohammad R., Majid Mahmood, Hafiz, Alshehri, Abdulaziz O., Alasmari, Fawaz F., Alqahtani, Faleh M., Alasmari, Abdullah F., Alsharari, Shakir D., Alhossan, Abdulaziz, Ahmad, Sheikh F., Nadeem, Ahmed, Alshammari, Tahani K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229333/
https://www.ncbi.nlm.nih.gov/pubmed/32435144
http://dx.doi.org/10.1016/j.jsps.2020.04.001