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Evaluation of new antihypertensive drugs designed in silico using Thermolysin as a target

The search for new therapies for the treatment of Arterial hypertension is a major concern in the scientific community. Here, we employ a computational biochemistry protocol to evaluate the performance of six compounds (Lig783, Lig1022, Lig1392, Lig2177, Lig3444 and Lig6199) to act as antihypertensi...

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Detalles Bibliográficos
Autores principales: MacLeod-Carey, Desmond, Solis-Céspedes, Eduardo, Lamazares, Emilio, Mena-Ulecia, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229335/
https://www.ncbi.nlm.nih.gov/pubmed/32435139
http://dx.doi.org/10.1016/j.jsps.2020.03.010