Hepatic expression of lipopolysaccharide-binding protein (Lbp) is induced by the gut microbiota through Myd88 and impairs glucose tolerance in mice independent of obesity

OBJECTIVE: Gut-derived inflammatory factors can impair glucose homeostasis, but the underlying mechanisms are not fully understood. In this study, we investigated how hepatic gene expression is regulated by gut colonization status through myeloid differentiation primary response 88 (MYD88) and how o...

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Detalles Bibliográficos
Autores principales: Molinaro, Antonio, Koh, Ara, Wu, Hao, Schoeler, Marc, Faggi, Maria Ilaria, Carreras, Alba, Hallén, Anna, Bäckhed, Fredrik, Caesar, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229497/
https://www.ncbi.nlm.nih.gov/pubmed/32305515
http://dx.doi.org/10.1016/j.molmet.2020.100997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229497/
https://www.ncbi.nlm.nih.gov/pubmed/32305515
http://dx.doi.org/10.1016/j.molmet.2020.100997

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