A widespread toxin−antitoxin system exploiting growth control via alarmone signaling

Under stressful conditions, bacterial RelA-SpoT Homolog (RSH) enzymes synthesize the alarmone (p)ppGpp, a nucleotide second messenger. (p)ppGpp rewires bacterial transcription and metabolism to cope with stress, and, at high concentrations, inhibits the process of protein synthesis and bacterial gro...

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Detalles Bibliográficos
Autores principales: Jimmy, Steffi, Saha, Chayan Kumar, Kurata, Tatsuaki, Stavropoulos, Constantine, Oliveira, Sofia Raquel Alves, Koh, Alan, Cepauskas, Albinas, Takada, Hiraku, Rejman, Dominik, Tenson, Tanel, Strahl, Henrik, Garcia-Pino, Abel, Hauryliuk, Vasili, Atkinson, Gemma C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229694/
https://www.ncbi.nlm.nih.gov/pubmed/32345719
http://dx.doi.org/10.1073/pnas.1916617117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229694/
https://www.ncbi.nlm.nih.gov/pubmed/32345719
http://dx.doi.org/10.1073/pnas.1916617117

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