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NORs on human acrocentric chromosome p-arms are active by default and can associate with nucleoli independently of rDNA

Nucleoli, the sites of ribosome biogenesis and the largest structures in human nuclei, form around nucleolar organizer regions (NORs) comprising ribosomal DNA (rDNA) arrays. NORs are located on the p-arms of the five human acrocentric chromosomes. Defining the rules of engagement between these p-arm...

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Detalles Bibliográficos
Autores principales: van Sluis, Marjolein, van Vuuren, Chelly, Mangan, Hazel, McStay, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229746/
https://www.ncbi.nlm.nih.gov/pubmed/32332163
http://dx.doi.org/10.1073/pnas.2001812117