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NORs on human acrocentric chromosome p-arms are active by default and can associate with nucleoli independently of rDNA
Nucleoli, the sites of ribosome biogenesis and the largest structures in human nuclei, form around nucleolar organizer regions (NORs) comprising ribosomal DNA (rDNA) arrays. NORs are located on the p-arms of the five human acrocentric chromosomes. Defining the rules of engagement between these p-arm...
Autores principales: | van Sluis, Marjolein, van Vuuren, Chelly, Mangan, Hazel, McStay, Brian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229746/ https://www.ncbi.nlm.nih.gov/pubmed/32332163 http://dx.doi.org/10.1073/pnas.2001812117 |
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