Ligand-dependent downregulation of MR1 cell surface expression

The antigen-presenting molecule MR1 presents riboflavin-based metabolites to Mucosal-Associated Invariant T (MAIT) cells. While MR1 egress to the cell surface is ligand-dependent, the ability of small-molecule ligands to impact on MR1 cellular trafficking remains unknown. Arising from an in silico s...

Descripción completa

Detalles Bibliográficos
Autores principales: Salio, Mariolina, Awad, Wael, Veerapen, Natacha, Gonzalez-Lopez, Claudia, Kulicke, Corinna, Waithe, Dominic, Martens, Anne W. J., Lewinsohn, David M., Hobrath, Judith V., Cox, Liam R., Rossjohn, Jamie, Besra, Gurdyal S., Cerundolo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229755/
https://www.ncbi.nlm.nih.gov/pubmed/32341160
http://dx.doi.org/10.1073/pnas.2003136117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229755/
https://www.ncbi.nlm.nih.gov/pubmed/32341160
http://dx.doi.org/10.1073/pnas.2003136117

Ejemplares similares