K6-linked SUMOylation of BAF regulates nuclear integrity and DNA replication in mammalian cells

Barrier-to-autointegration factor (BAF) is a highly conserved protein in metazoans that has multiple functions during the cell cycle. We found that BAF is SUMOylated at K6, and that this modification is essential for its nuclear localization and function, including nuclear integrity maintenance and...

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Detalles Bibliográficos
Autores principales: Lin, Qiaoyu, Yu, Bin, Wang, Xiangyang, Zhu, Shicong, Zhao, Gan, Jia, Mingkang, Huang, Fan, Xu, Nan, Ren, He, Jiang, Qing, Zhang, Chuanmao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229763/
https://www.ncbi.nlm.nih.gov/pubmed/32332162
http://dx.doi.org/10.1073/pnas.1912984117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229763/
https://www.ncbi.nlm.nih.gov/pubmed/32332162
http://dx.doi.org/10.1073/pnas.1912984117

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