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K6-linked SUMOylation of BAF regulates nuclear integrity and DNA replication in mammalian cells
Barrier-to-autointegration factor (BAF) is a highly conserved protein in metazoans that has multiple functions during the cell cycle. We found that BAF is SUMOylated at K6, and that this modification is essential for its nuclear localization and function, including nuclear integrity maintenance and...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229763/ https://www.ncbi.nlm.nih.gov/pubmed/32332162 http://dx.doi.org/10.1073/pnas.1912984117 |