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Pranlukast Antagonizes CD49f and Reduces Stemness in Triple-Negative Breast Cancer Cells

INTRODUCTION: Cancer stem cells (CSCs) drive the initiation, maintenance, and therapy response of breast tumors. CD49f is expressed in breast CSCs and functions in the maintenance of stemness. Thus, blockade of CD49f is a potential therapeutic approach for targeting breast CSCs. In the present stu...

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Detalles Bibliográficos
Autores principales: Velázquez-Quesada, Inés, Ruiz-Moreno, Angel J, Casique-Aguirre, Diana, Aguirre-Alvarado, Charmina, Cortés-Mendoza, Fabiola, de la Fuente-Granada, Marisol, García-Pérez, Carlos, Pérez-Tapia, Sonia M, González-Arenas, Aliesha, Segura-Cabrera, Aldo, Velasco-Velázquez, Marco A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229803/
https://www.ncbi.nlm.nih.gov/pubmed/32494122
http://dx.doi.org/10.2147/DDDT.S247730