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ATP serves as a nucleotide switch coupling the genome maturation and packaging motor complexes of a virus assembly machine
The assembly of double-stranded DNA viruses, from phages to herpesviruses, is strongly conserved. Terminase enzymes processively excise and package monomeric genomes from a concatemeric DNA substrate. The enzymes cycle between a stable maturation complex that introduces site-specific nicks into the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229814/ https://www.ncbi.nlm.nih.gov/pubmed/32255177 http://dx.doi.org/10.1093/nar/gkaa205 |