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ATP serves as a nucleotide switch coupling the genome maturation and packaging motor complexes of a virus assembly machine

The assembly of double-stranded DNA viruses, from phages to herpesviruses, is strongly conserved. Terminase enzymes processively excise and package monomeric genomes from a concatemeric DNA substrate. The enzymes cycle between a stable maturation complex that introduces site-specific nicks into the...

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Detalles Bibliográficos
Autores principales: Yang, Qin, Catalano, Carlos E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229814/
https://www.ncbi.nlm.nih.gov/pubmed/32255177
http://dx.doi.org/10.1093/nar/gkaa205