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Specific histone modifications associate with alternative exon selection during mammalian development

Alternative splicing (AS) is frequent during early mouse embryonic development. Specific histone post-translational modifications (hPTMs) have been shown to regulate exon splicing by either directly recruiting splice machinery or indirectly modulating transcriptional elongation. In this study, we hy...

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Detalles Bibliográficos
Autores principales: Hu, Qiwen, Greene, Casey S, Heller, Elizabeth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229819/
https://www.ncbi.nlm.nih.gov/pubmed/32319526
http://dx.doi.org/10.1093/nar/gkaa248