Nono deficiency compromises TET1 chromatin association and impedes neuronal differentiation of mouse embryonic stem cells

NONO is a DNA/RNA-binding protein, which plays a critical regulatory role during cell stage transitions of mouse embryonic stem cells (mESCs). However, its function in neuronal lineage commitment and the molecular mechanisms of its action in such processes are largely unknown. Here we report that NO...

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Detalles Bibliográficos
Autores principales: Li, Wenjing, Karwacki-Neisius, Violetta, Ma, Chun, Tan, Li, Shi, Yang, Wu, Feizhen, Shi, Yujiang Geno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229820/
https://www.ncbi.nlm.nih.gov/pubmed/32286661
http://dx.doi.org/10.1093/nar/gkaa213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229820/
https://www.ncbi.nlm.nih.gov/pubmed/32286661
http://dx.doi.org/10.1093/nar/gkaa213

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