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Nono deficiency compromises TET1 chromatin association and impedes neuronal differentiation of mouse embryonic stem cells
NONO is a DNA/RNA-binding protein, which plays a critical regulatory role during cell stage transitions of mouse embryonic stem cells (mESCs). However, its function in neuronal lineage commitment and the molecular mechanisms of its action in such processes are largely unknown. Here we report that NO...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229820/ https://www.ncbi.nlm.nih.gov/pubmed/32286661 http://dx.doi.org/10.1093/nar/gkaa213 |