The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt–PCAF pathway in promotion of esophageal squamous cell carcinoma growth

High-mobility group AT-hook 2 (HMGA2) is an architectural transcription factor that plays essential roles in embryonic development and cancer progression. However, the mechanism of HMGA2 regulation remains largely uncharacterized. Here, we demonstrate that HMGA2 can be modulated by hepatitis B X-int...

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Detalles Bibliográficos
Autores principales: Wu, Yue, Wang, Xue, Xu, Feifei, Zhang, Lu, Wang, Tianjiao, Fu, Xueli, Jin, Tianzhi, Zhang, Weiying, Ye, Lihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229824/
https://www.ncbi.nlm.nih.gov/pubmed/32313942
http://dx.doi.org/10.1093/nar/gkaa232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229824/
https://www.ncbi.nlm.nih.gov/pubmed/32313942
http://dx.doi.org/10.1093/nar/gkaa232

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