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Release of promoter–proximal paused Pol II in response to histone deacetylase inhibition

A correlation between histone acetylation and transcription has been noted for a long time, but little is known about what step(s) in the transcription cycle is influenced by acetylation. We have examined the immediate transcriptional response to histone deacetylase (HDAC) inhibition, and find that...

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Detalles Bibliográficos
Autores principales: Vaid, Roshan, Wen, Jiayu, Mannervik, Mattias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229826/
https://www.ncbi.nlm.nih.gov/pubmed/32297950
http://dx.doi.org/10.1093/nar/gkaa234