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Release of promoter–proximal paused Pol II in response to histone deacetylase inhibition
A correlation between histone acetylation and transcription has been noted for a long time, but little is known about what step(s) in the transcription cycle is influenced by acetylation. We have examined the immediate transcriptional response to histone deacetylase (HDAC) inhibition, and find that...
Autores principales: | Vaid, Roshan, Wen, Jiayu, Mannervik, Mattias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229826/ https://www.ncbi.nlm.nih.gov/pubmed/32297950 http://dx.doi.org/10.1093/nar/gkaa234 |
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