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EXO1 resection at G-quadruplex structures facilitates resolution and replication

G-quadruplexes represent unique roadblocks to DNA replication, which tends to stall at these secondary structures. Although G-quadruplexes can be found throughout the genome, telomeres, due to their G-richness, are particularly predisposed to forming these structures and thus represent difficult-to-...

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Detalles Bibliográficos
Autores principales: Stroik, Susanna, Kurtz, Kevin, Lin, Kevin, Karachenets, Sergey, Myers, Chad L, Bielinsky, Anja-Katrin, Hendrickson, Eric A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229832/
https://www.ncbi.nlm.nih.gov/pubmed/32232411
http://dx.doi.org/10.1093/nar/gkaa199