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Functional organization of box C/D RNA-guided RNA methyltransferase

Box C/D RNA protein complexes (RNPs) catalyze site-specific 2′-O-methylation of RNA with specificity determined by guide RNAs. In eukaryotic C/D RNP, the paralogous Nop58 and Nop56 proteins specifically associate with terminal C/D and internal C'/D' motifs of guide RNAs, respectively. We h...

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Detalles Bibliográficos
Autores principales: Yang, Zuxiao, Wang, Jiayin, Huang, Lin, Lilley, David M J, Ye, Keqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229835/
https://www.ncbi.nlm.nih.gov/pubmed/32297938
http://dx.doi.org/10.1093/nar/gkaa247