Uncovering the cellular capacity for intensive and specific feedback self-control of the argonautes and MicroRNA targeting activity

The miRNA pathway has three segments—biogenesis, targeting and downstream regulatory effectors. We aimed to better understand their cellular control by exploring the miRNA-mRNA-targeting relationships. We first used human evolutionarily conserved sites. Strikingly, AGOs 1–3 are all among the top 14...

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Detalles Bibliográficos
Autores principales: Wang, Degeng, Wang, Tingzeng, Gill, Audrey, Hilliard, Terrell, Chen, Fengqian, Karamyshev, Andrey L, Zhang, Fangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229836/
https://www.ncbi.nlm.nih.gov/pubmed/32297952
http://dx.doi.org/10.1093/nar/gkaa209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229836/
https://www.ncbi.nlm.nih.gov/pubmed/32297952
http://dx.doi.org/10.1093/nar/gkaa209

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