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Uncovering the cellular capacity for intensive and specific feedback self-control of the argonautes and MicroRNA targeting activity
The miRNA pathway has three segments—biogenesis, targeting and downstream regulatory effectors. We aimed to better understand their cellular control by exploring the miRNA-mRNA-targeting relationships. We first used human evolutionarily conserved sites. Strikingly, AGOs 1–3 are all among the top 14...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229836/ https://www.ncbi.nlm.nih.gov/pubmed/32297952 http://dx.doi.org/10.1093/nar/gkaa209 |