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Genetic interactions and transcriptomics implicate fission yeast CTD prolyl isomerase Pin1 as an agent of RNA 3′ processing and transcription termination that functions via its effects on CTD phosphatase Ssu72

The phosphorylation pattern of Pol2 CTD Y(1)S(2)P(3)T(4)S(5)P(6)S(7) repeats comprises an informational code coordinating transcription and RNA processing. cis–trans isomerization of CTD prolines expands the scope of the code in ways that are not well understood. Here we address this issue via analy...

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Detalles Bibliográficos
Autores principales: Sanchez, Ana M, Garg, Angad, Shuman, Stewart, Schwer, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229847/
https://www.ncbi.nlm.nih.gov/pubmed/32282918
http://dx.doi.org/10.1093/nar/gkaa212