Selective targeting of mutually exclusive DNA G-quadruplexes: HIV-1 LTR as paradigmatic model

Targeting of G-quadruplexes, non-canonical conformations that form in G-rich regions of nucleic acids, has been proposed as a novel therapeutic strategy toward several diseases, including cancer and infections. The unavailability of highly selective molecules targeting a G-quadruplex of choice has h...

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Detalles Bibliográficos
Autores principales: Tassinari, Martina, Zuffo, Michela, Nadai, Matteo, Pirota, Valentina, Sevilla Montalvo, Adriana Carolina, Doria, Filippo, Freccero, Mauro, Richter, Sara N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229848/
https://www.ncbi.nlm.nih.gov/pubmed/32282912
http://dx.doi.org/10.1093/nar/gkaa186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229848/
https://www.ncbi.nlm.nih.gov/pubmed/32282912
http://dx.doi.org/10.1093/nar/gkaa186

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