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Selective targeting of mutually exclusive DNA G-quadruplexes: HIV-1 LTR as paradigmatic model
Targeting of G-quadruplexes, non-canonical conformations that form in G-rich regions of nucleic acids, has been proposed as a novel therapeutic strategy toward several diseases, including cancer and infections. The unavailability of highly selective molecules targeting a G-quadruplex of choice has h...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229848/ https://www.ncbi.nlm.nih.gov/pubmed/32282912 http://dx.doi.org/10.1093/nar/gkaa186 |