Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction

Disabling hearing loss impacts ∼466 million individuals worldwide with 34 million children affected. Gene and pharmacotherapeutic strategies to rescue auditory function in mouse models of human deafness are most effective when administered before hearing onset, after which therapeutic efficacy is si...

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Detalles Bibliográficos
Autores principales: Wang, Lingyan, Kempton, J Beth, Jiang, Han, Jodelka, Francine M, Brigande, Alev M, Dumont, Rachel A, Rigo, Frank, Lentz, Jennifer J, Hastings, Michelle L, Brigande, John V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229850/
https://www.ncbi.nlm.nih.gov/pubmed/32249312
http://dx.doi.org/10.1093/nar/gkaa194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229850/
https://www.ncbi.nlm.nih.gov/pubmed/32249312
http://dx.doi.org/10.1093/nar/gkaa194

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