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Computational identification of cell-specific variable regions in ChIP-seq data

Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is used to identify genome-wide DNA regions bound by proteins. Given one ChIP-seq experiment with replicates, binding sites not observed in all the replicates will usually be interpreted as noise and discarded. However, the recent disco...

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Detalles Bibliográficos
Autores principales: Andreani, Tommaso, Albrecht, Steffen, Fontaine, Jean-Fred, Andrade-Navarro, Miguel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229859/
https://www.ncbi.nlm.nih.gov/pubmed/32187374
http://dx.doi.org/10.1093/nar/gkaa180