Retrospective clinical trial experimentally validates glioblastoma genome-wide pattern of DNA copy-number alterations predictor of survival

Modeling of genomic profiles from the Cancer Genome Atlas (TCGA) by using recently developed mathematical frameworks has associated a genome-wide pattern of DNA copy-number alterations with a shorter, roughly one-year, median survival time in glioblastoma (GBM) patients. Here, to experimentally test...

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Detalles Bibliográficos
Autores principales: Ponnapalli, Sri Priya, Bradley, Matthew W., Devine, Karen, Bowen, Jay, Coppens, Sara E., Leraas, Kristen M., Milash, Brett A., Li, Fuqiang, Luo, Huijuan, Qiu, Shi, Wu, Kui, Yang, Huanming, Wittwer, Carl T., Palmer, Cheryl A., Jensen, Randy L., Gastier-Foster, Julie M., Hanson, Heidi A., Barnholtz-Sloan, Jill S., Alter, Orly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229984/
https://www.ncbi.nlm.nih.gov/pubmed/32478280
http://dx.doi.org/10.1063/1.5142559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229984/
https://www.ncbi.nlm.nih.gov/pubmed/32478280
http://dx.doi.org/10.1063/1.5142559

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