Mechanism of selective anticancer activity of isothiocyanates relies on differences in DNA damage repair between cancer and healthy cells

PURPOSE: Isothiocyanates (ITCs) are compounds derived from Brassica plants with documented anticancer activity. Molecular mechanisms of their selective activity against cancer cells are still underexplored. In this work, the impact of ITC on DNA replication and damage was compared between PC-3 prost...

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Detalles Bibliográficos
Autores principales: Hać, Aleksandra, Brokowska, Joanna, Rintz, Estera, Bartkowski, Michał, Węgrzyn, Grzegorz, Herman-Antosiewicz, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230056/
https://www.ncbi.nlm.nih.gov/pubmed/31123866
http://dx.doi.org/10.1007/s00394-019-01995-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230056/
https://www.ncbi.nlm.nih.gov/pubmed/31123866
http://dx.doi.org/10.1007/s00394-019-01995-6

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