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Oncolytic Newcastle disease virus activation of the innate immune response and priming of antitumor adaptive responses in vitro

Oncolytic virus (OV) therapy is an emerging approach with the potential to redefine treatment options across a range of cancer indications and in patients who remain resistant to existing standards of care, including immuno-oncology (IO) drugs. MEDI5395, a recombinant Newcastle disease virus (NDV),...

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Detalles Bibliográficos
Autores principales: Burke, Shannon, Shergold, Amy, Elder, Matthew J., Whitworth, Justine, Cheng, Xing, Jin, Hong, Wilkinson, Robert W., Harper, James, Carroll, Danielle K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230062/
https://www.ncbi.nlm.nih.gov/pubmed/32088771
http://dx.doi.org/10.1007/s00262-020-02495-x