Cargando…

Oncolytic Newcastle disease virus activation of the innate immune response and priming of antitumor adaptive responses in vitro

Oncolytic virus (OV) therapy is an emerging approach with the potential to redefine treatment options across a range of cancer indications and in patients who remain resistant to existing standards of care, including immuno-oncology (IO) drugs. MEDI5395, a recombinant Newcastle disease virus (NDV),...

Descripción completa

Detalles Bibliográficos
Autores principales:	Burke, Shannon, Shergold, Amy, Elder, Matthew J., Whitworth, Justine, Cheng, Xing, Jin, Hong, Wilkinson, Robert W., Harper, James, Carroll, Danielle K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230062/ https://www.ncbi.nlm.nih.gov/pubmed/32088771 http://dx.doi.org/10.1007/s00262-020-02495-x

Ejemplares similares

Recombinant Newcastle Disease Virus Immunotherapy Drives Oncolytic Effects and Durable Systemic Antitumor Immunity
por: Harper, James, et al.
Publicado: (2021)

Recombinant oncolytic Newcastle disease virus displays antitumor activities in anaplastic thyroid cancer cells
por: Jiang, Ke, et al.
Publicado: (2018)

Engaging the Innate and Adaptive Antitumor Immune Response in Lymphoma
por: Csizmar, Clifford M., et al.
Publicado: (2021)

An oncolytic virus expressing a full-length antibody enhances antitumor innate immune response to glioblastoma
por: Xu, Bo, et al.
Publicado: (2021)

Adaptation of the Newcastle Disease Virus to Cell Cultures for Enhancing Its Oncolytic Properties
por: Yurchenko, K. S., et al.
Publicado: (2019)

A recombinant oncolytic Newcastle virus expressing MIP-3α promotes systemic antitumor immunity
por: Huang, Feng-Ying, et al.
Publicado: (2020)

Induction of antitumor response to fibrosarcoma by Newcastle disease virus-infected tumor vaccine
por: Takamura-Ishii, Mai, et al.
Publicado: (2017)

Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101
por: Scholz, Alexander, et al.
Publicado: (2022)

Type 1 Innate Lymphoid Cells Limit the Antitumoral Immune Response
por: Vienne, Margaux, et al.
Publicado: (2021)

Host Innate Immune Responses of Ducks Infected with Newcastle Disease Viruses of Different Pathogenicities
por: Kang, Yinfeng, et al.
Publicado: (2015)

Transcriptional Innate Immune Response of the Developing Chicken Embryo to Newcastle Disease Virus Infection
por: Schilling, Megan A., et al.
Publicado: (2018)

Oncolytic Newcastle Disease Virus as Cutting Edge between Tumor and Host
por: Fournier, Philippe, et al.
Publicado: (2013)

Therapeutic potential of oncolytic Newcastle disease virus: a critical review
por: Tayeb, Shay, et al.
Publicado: (2015)

The Viral Knock: Ameliorating Cancer Treatment with Oncolytic Newcastle Disease Virus
por: Pathak, Upasana, et al.
Publicado: (2023)

Updates to the antitumor mechanism of oncolytic virus
por: Bai, Yang, et al.
Publicado: (2019)

Development of Molecular Mechanisms and Their Application on Oncolytic Newcastle Disease Virus in Cancer Therapy
por: Huang, Fang, et al.
Publicado: (2022)

Counteracting Immunosuppression in the Tumor Microenvironment by Oncolytic Newcastle Disease Virus and Cellular Immunotherapy
por: Schirrmacher, Volker, et al.
Publicado: (2022)

Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response
por: West, A. Phillip, et al.
Publicado: (2015)

Chronic stress primes innate immune responses in mice and humans
por: Barrett, Tessa J., et al.
Publicado: (2021)

Bridging Innate and Adaptive Antitumor Immunity Targeting Glycans
por: Pashov, Anastas, et al.
Publicado: (2010)

Oncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity
por: Leddon, Jennifer L, et al.
Publicado: (2015)

Optimization of oncolytic effect of Newcastle disease virus Clone30 by selecting sensitive tumor host and constructing more oncolytic viruses
por: Liu, Tianyan, et al.
Publicado: (2020)

Oncolytic Viruses: Priming Time for Cancer Immunotherapy
por: Russell, Luke, et al.
Publicado: (2019)

A spontaneous multifunctional hydrogel vaccine amplifies the innate immune response to launch a powerful antitumor adaptive immune response
por: Liang, Xiuqi, et al.
Publicado: (2021)

Differential regulation of innate and adaptive immune responses in viral encephalitis
por: Rempel, Julia D., et al.
Publicado: (2004)

Two is better than one: Complementing oncolytic virotherapy with gemcitabine to potentiate antitumor immune responses
por: Gujar, Shashi A, et al.
Publicado: (2014)

The Novel Oncolytic Compound LTX-401 Induces Antitumor Immune Responses in Experimental Hepatocellular Carcinoma
por: Mauseth, Brynjar, et al.
Publicado: (2019)

Induction of Durable Antitumor Response by a Novel Oncolytic Herpesvirus Expressing Multiple Immunomodulatory Transgenes
por: Chouljenko, Dmitry V., et al.
Publicado: (2020)

Intraperitoneal oncolytic virotherapy for patients with malignant ascites: Characterization of clinical efficacy and antitumor immune response
por: Zhang, Yalei, et al.
Publicado: (2022)

Recombinant Immunomodulating Lentogenic or Mesogenic Oncolytic Newcastle Disease Virus for Treatment of Pancreatic Adenocarcinoma
por: Buijs, Pascal, et al.
Publicado: (2015)

Breaking Therapy Resistance: An Update on Oncolytic Newcastle Disease Virus for Improvements of Cancer Therapy
por: Schirrmacher, Volker, et al.
Publicado: (2019)

Oncolytic Newcastle disease virus reduces growth of cervical cancer cell by inducing apoptosis
por: Keshavarz, Mohsen, et al.
Publicado: (2020)

Molecular Mechanisms of Anti-Neoplastic and Immune Stimulatory Properties of Oncolytic Newcastle Disease Virus
por: Schirrmacher, Volker
Publicado: (2022)

Investigation of oncolytic effect of recombinant Newcastle disease virus in primary and metastatic oral melanoma
por: Numpadit, Supaporn, et al.
Publicado: (2023)

Papaverine Enhances the Oncolytic Effects of Newcastle Disease Virus on Breast Cancer In Vitro and In Vivo
por: Akram, Sura, et al.
Publicado: (2023)

Aptamers Enhance Oncolytic Viruses’ Antitumor Efficacy
por: Dymova, Maya A., et al.
Publicado: (2022)

Strong innate immune response and cell death in chicken splenocytes infected with genotype VIId Newcastle disease virus
por: Hu, Zenglei, et al.
Publicado: (2012)

ATM-mediated DNA double-strand break response facilitated oncolytic Newcastle disease virus replication and promoted syncytium formation in tumor cells
por: Ren, Shanhui, et al.
Publicado: (2020)

Cholesterol metabolism in innate and adaptive response
por: Reboldi, Andrea, et al.
Publicado: (2018)

The Role of the Innate Immune System in Oncolytic Virotherapy
por: Phan, Tuan Anh, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1v52enst8sg60jg4e8vuj1fkj2