Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress

A key reason for the persistently grim statistics associated with metastatic ovarian cancer is resistance to conventional agents, including platinum-based chemotherapies. A major source of treatment failure is the high degree of genetic and molecular heterogeneity, which results from significant und...

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Detalles Bibliográficos
Autores principales: Nath, Shubhankar, Pigula, Michael, Khan, Amjad P., Hanna, William, Ruhi, Mustafa Kemal, Dehkordy, Farzaneh Mahmoodpoor, Pushpavanam, Karthik, Rege, Kaushal, Moore, Kaitlin, Tsujita, Yujiro, Conrad, Christina, Inci, Fatih, del Carmen, Marcela G., Franco, Walfre, Celli, Jonathan P., Demirci, Utkan, Hasan, Tayyaba, Huang, Huang-Chiao, Rizvi, Imran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230263/
https://www.ncbi.nlm.nih.gov/pubmed/32231055
http://dx.doi.org/10.3390/jcm9040924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230263/
https://www.ncbi.nlm.nih.gov/pubmed/32231055
http://dx.doi.org/10.3390/jcm9040924

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