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Characterization of Regulatory and Transporter Genes in the Biosynthesis of Anti-Tuberculosis Ilamycins and Production in a Heterologous Host

Ilamycins are cyclopeptides with novel structures that have been isolated from different Actinomycetes. They showed strong anti-tuberculosis activity and could serve as important anti-tuberculosis drug leads. The functions of the pre-tailoring and the post-tailoring genes in the biosynthesis of ilam...

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Detalles Bibliográficos
Autores principales: He, Jianqiao, Wei, Xin, Yang, Zhijie, Li, Yan, Ju, Jianhua, Ma, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230496/
https://www.ncbi.nlm.nih.gov/pubmed/32316457
http://dx.doi.org/10.3390/md18040216