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Transcriptomic Profiling Identifies Differentially Expressed Genes in Palbociclib-Resistant ER+ MCF7 Breast Cancer Cells

Acquired resistance to cyclin-dependent kinases 4 and 6 (CDK4/6) inhibition in estrogen receptor-positive (ER+) breast cancer remains a significant clinical challenge. Efforts to uncover the mechanisms underlying resistance are needed to establish clinically actionable targets effective against resi...

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Detalles Bibliográficos
Autores principales: Lanceta, Lilibeth, O’Neill, Conor, Lypova, Nadiia, Li, Xiahong, Rouchka, Eric, Waigel, Sabine, Gomez-Gutierrez, Jorge G., Chesney, Jason, Imbert-Fernandez, Yoannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230561/
https://www.ncbi.nlm.nih.gov/pubmed/32344635
http://dx.doi.org/10.3390/genes11040467