Cargando…

Effects of Ashwagandha (Withania somnifera) on VO(2max): A Systematic Review and Meta-Analysis

The purpose of this study was to systematically review the scientific literature about the effects of supplementation with Ashwagandha (Withania somnifera) on maximum oxygen consumption (VO(2max)), as well as to provide directions for clinical practice. A systematic search was conducted in three ele...

Descripción completa

Detalles Bibliográficos
Autores principales: Pérez-Gómez, Jorge, Villafaina, Santos, Adsuar, José Carmelo, Merellano-Navarro, Eugenio, Collado-Mateo, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230697/
https://www.ncbi.nlm.nih.gov/pubmed/32316411
http://dx.doi.org/10.3390/nu12041119
_version_ 1783535015732183040
author Pérez-Gómez, Jorge
Villafaina, Santos
Adsuar, José Carmelo
Merellano-Navarro, Eugenio
Collado-Mateo, Daniel
author_facet Pérez-Gómez, Jorge
Villafaina, Santos
Adsuar, José Carmelo
Merellano-Navarro, Eugenio
Collado-Mateo, Daniel
author_sort Pérez-Gómez, Jorge
collection PubMed
description The purpose of this study was to systematically review the scientific literature about the effects of supplementation with Ashwagandha (Withania somnifera) on maximum oxygen consumption (VO(2max)), as well as to provide directions for clinical practice. A systematic search was conducted in three electronic databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA). The inclusion criteria were: (a) VO(2max) data, with means ± standard deviation before and after the supplement intervention, (b) the study was randomized controlled trial (RCT), (c) the article was written in English. The quality of evidence was evaluated according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. A meta-analysis was performed to determine effect sizes. Five studies were selected in the systematic review (162 participants) and four were included in the meta-analysis (142 participants). Results showed a significant enhancement in VO(2max) in healthy adults and athletes (p = 0.04). The mean difference was 3.00 (95% CI from 0.18 to 5.82) with high heterogeneity. In conclusion, Ashwagandha supplementation might improve the VO(2max) in athlete and non-athlete people. However, further research is need to confirm this hypothesis since the number of studies is limited and the heterogeneity was high.
format Online
Article
Text
id pubmed-7230697
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-72306972020-05-22 Effects of Ashwagandha (Withania somnifera) on VO(2max): A Systematic Review and Meta-Analysis Pérez-Gómez, Jorge Villafaina, Santos Adsuar, José Carmelo Merellano-Navarro, Eugenio Collado-Mateo, Daniel Nutrients Communication The purpose of this study was to systematically review the scientific literature about the effects of supplementation with Ashwagandha (Withania somnifera) on maximum oxygen consumption (VO(2max)), as well as to provide directions for clinical practice. A systematic search was conducted in three electronic databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA). The inclusion criteria were: (a) VO(2max) data, with means ± standard deviation before and after the supplement intervention, (b) the study was randomized controlled trial (RCT), (c) the article was written in English. The quality of evidence was evaluated according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. A meta-analysis was performed to determine effect sizes. Five studies were selected in the systematic review (162 participants) and four were included in the meta-analysis (142 participants). Results showed a significant enhancement in VO(2max) in healthy adults and athletes (p = 0.04). The mean difference was 3.00 (95% CI from 0.18 to 5.82) with high heterogeneity. In conclusion, Ashwagandha supplementation might improve the VO(2max) in athlete and non-athlete people. However, further research is need to confirm this hypothesis since the number of studies is limited and the heterogeneity was high. MDPI 2020-04-17 /pmc/articles/PMC7230697/ /pubmed/32316411 http://dx.doi.org/10.3390/nu12041119 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Pérez-Gómez, Jorge
Villafaina, Santos
Adsuar, José Carmelo
Merellano-Navarro, Eugenio
Collado-Mateo, Daniel
Effects of Ashwagandha (Withania somnifera) on VO(2max): A Systematic Review and Meta-Analysis
title Effects of Ashwagandha (Withania somnifera) on VO(2max): A Systematic Review and Meta-Analysis
title_full Effects of Ashwagandha (Withania somnifera) on VO(2max): A Systematic Review and Meta-Analysis
title_fullStr Effects of Ashwagandha (Withania somnifera) on VO(2max): A Systematic Review and Meta-Analysis
title_full_unstemmed Effects of Ashwagandha (Withania somnifera) on VO(2max): A Systematic Review and Meta-Analysis
title_short Effects of Ashwagandha (Withania somnifera) on VO(2max): A Systematic Review and Meta-Analysis
title_sort effects of ashwagandha (withania somnifera) on vo(2max): a systematic review and meta-analysis
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230697/
https://www.ncbi.nlm.nih.gov/pubmed/32316411
http://dx.doi.org/10.3390/nu12041119
work_keys_str_mv AT perezgomezjorge effectsofashwagandhawithaniasomniferaonvo2maxasystematicreviewandmetaanalysis
AT villafainasantos effectsofashwagandhawithaniasomniferaonvo2maxasystematicreviewandmetaanalysis
AT adsuarjosecarmelo effectsofashwagandhawithaniasomniferaonvo2maxasystematicreviewandmetaanalysis
AT merellanonavarroeugenio effectsofashwagandhawithaniasomniferaonvo2maxasystematicreviewandmetaanalysis
AT colladomateodaniel effectsofashwagandhawithaniasomniferaonvo2maxasystematicreviewandmetaanalysis