Marine-Inspired Bis-indoles Possessing Antiproliferative Activity against Breast Cancer; Design, Synthesis, and Biological Evaluation

Diverse indoles and bis-indoles extracted from marine sources have been identified as promising anticancer leads. Herein, we designed and synthesized novel bis-indole series 7a–f and 9a–h as Topsentin and Nortopsentin analogs. Our design is based on replacing the heterocyclic spacer in the natural l...

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Detalles Bibliográficos
Autores principales: Eldehna, Wagdy M., Hassan, Ghada S., Al-Rashood, Sara T., Alkahtani, Hamad M., A. Almehizia, Abdulrahman, Al-Ansary, Ghada H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230731/
https://www.ncbi.nlm.nih.gov/pubmed/32252280
http://dx.doi.org/10.3390/md18040190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230731/
https://www.ncbi.nlm.nih.gov/pubmed/32252280
http://dx.doi.org/10.3390/md18040190

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