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Kaempferide Enhances Chemosensitivity of Human Lung Adenocarcinoma A549 Cells Mediated by the Decrease in Phosphorylation of Akt and Claudin-2 Expression

Claudins (CLDNs) play crucial roles in the formation of tight junctions. We have reported that abnormal expression of CLDN2 confers chemoresistance in the spheroids of human lung adenocarcinoma A549 cells. A food composition, which can reduce CLDN2 expression, may function to prevent the malignant p...

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Detalles Bibliográficos
Autores principales: Eguchi, Hiroaki, Matsunaga, Toshiyuki, Endo, Satoshi, Ichihara, Kenji, Ikari, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230790/
https://www.ncbi.nlm.nih.gov/pubmed/32340376
http://dx.doi.org/10.3390/nu12041190