Cytotoxic Activity of Aplykurodin A Isolated From Aplysia kurodai against AXIN1-Mutated Hepatocellular Carcinoma Cells by Promoting Oncogenic β-Catenin Degradation

Dysregulation of the Wnt/β-catenin signaling pathway is involved in the development of human hepatocellular carcinoma and has thus emerged as a therapeutic target for this malignant tumor. In this study, we employed sensitive cell-based assays to identify aplykurodin A isolated from Aplysia kurodai...

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Detalles Bibliográficos
Autores principales: Lee, Jaehoo, Zhou, Wei, Na, MinKyun, Oh, Sangtaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230895/
https://www.ncbi.nlm.nih.gov/pubmed/32294900
http://dx.doi.org/10.3390/md18040210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230895/
https://www.ncbi.nlm.nih.gov/pubmed/32294900
http://dx.doi.org/10.3390/md18040210

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