Effects of Cyclization on Activity and Stability of α-Conotoxin TxIB

α-Conotoxin TxIB specifically blocked α6/α3β2β3 acetylcholine receptors (nAChRs), and it could be a potential probe for studying addiction and other diseases related to α6/α3β2β3 nAChRs. However, as a peptide, TxIB may suffer from low stability, short half-life, and poor bioavailability. In this stu...

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Detalles Bibliográficos
Autores principales: Li, Xincan, Wang, Shuai, Zhu, Xiaopeng, Zhangsun, Dongting, Wu, Yong, Luo, Sulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230940/
https://www.ncbi.nlm.nih.gov/pubmed/32235388
http://dx.doi.org/10.3390/md18040180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230940/
https://www.ncbi.nlm.nih.gov/pubmed/32235388
http://dx.doi.org/10.3390/md18040180

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