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Effects of Cyclization on Activity and Stability of α-Conotoxin TxIB

α-Conotoxin TxIB specifically blocked α6/α3β2β3 acetylcholine receptors (nAChRs), and it could be a potential probe for studying addiction and other diseases related to α6/α3β2β3 nAChRs. However, as a peptide, TxIB may suffer from low stability, short half-life, and poor bioavailability. In this stu...

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Detalles Bibliográficos
Autores principales:	Li, Xincan, Wang, Shuai, Zhu, Xiaopeng, Zhangsun, Dongting, Wu, Yong, Luo, Sulan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230940/ https://www.ncbi.nlm.nih.gov/pubmed/32235388 http://dx.doi.org/10.3390/md18040180

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