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SLC22A1 rs622342 Polymorphism Predicts Insulin Resistance Improvement in Patients with Type 2 Diabetes Mellitus Treated with Metformin: A Cross-Sectional Study

BACKGROUND: Metformin is the most widely used oral antidiabetic agent and can reduce insulin resistance (IR) effectively. Organic cation transporter 1 (encoded by SLC22A1) is responsible for the transport of metformin, and ataxia-telangiectasia-mutated (ATM) is a gene relating to the DNA repair and...

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Detalles Bibliográficos
Autores principales: Wu, Kunrong, Li, Xiaoli, Xu, Yuedong, Zhang, Xiaoqian, Guan, Ziwan, Zhang, Shufang, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231067/
https://www.ncbi.nlm.nih.gov/pubmed/32454819
http://dx.doi.org/10.1155/2020/2975898