CDH1 Mutation Distribution and Type Suggests Genetic Differences between the Etiology of Orofacial Clefting and Gastric Cancer

Pathogenic variants in CDH1, encoding epithelial cadherin (E-cadherin), have been implicated in hereditary diffuse gastric cancer (HDGC), lobular breast cancer, and both syndromic and non-syndromic cleft lip/palate (CL/P). Despite the large number of CDH1 mutations described, the nature of the pheno...

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Detalles Bibliográficos
Autores principales: Selvanathan, Arthavan, Nixon, Cheng Yee, Zhu, Ying, Scietti, Luigi, Forneris, Federico, Moreno Uribe, Lina M., Lidral, Andrew C., Jezewski, Peter A., Mulliken, John B., Murray, Jeffrey C., Buckley, Michael F., Cox, Timothy C., Roscioli, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231129/
https://www.ncbi.nlm.nih.gov/pubmed/32260281
http://dx.doi.org/10.3390/genes11040391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231129/
https://www.ncbi.nlm.nih.gov/pubmed/32260281
http://dx.doi.org/10.3390/genes11040391

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