Cargando…

Arginine Auxotrophy Affects Siderophore Biosynthesis and Attenuates Virulence of Aspergillus fumigatus

Aspergillus fumigatus is an opportunistic human pathogen mainly infecting immunocompromised patients. The aim of this study was to characterize the role of arginine biosynthesis in virulence of A. fumigatus via genetic inactivation of two key arginine biosynthetic enzymes, the bifunctional acetylglu...

Descripción completa

Detalles Bibliográficos
Autores principales: Dietl, Anna-Maria, Binder, Ulrike, Bauer, Ingo, Shadkchan, Yana, Osherov, Nir, Haas, Hubertus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231135/
https://www.ncbi.nlm.nih.gov/pubmed/32326414
http://dx.doi.org/10.3390/genes11040423