Metabolic Switching of Tumor Cells under Hypoxic Conditions in a Tumor-on-a-chip Model

Hypoxia switches the metabolism of tumor cells and induces drug resistance. Currently, no therapeutic exists that effectively and specifically targets hypoxic cells in tumors. Development of such therapeutics critically depends on the availability of in vitro models that accurately recapitulate hypo...

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Detalles Bibliográficos
Autores principales: Palacio-Castañeda, Valentina, Kooijman, Lucas, Venzac, Bastien, Verdurmen, Wouter P.R., Le Gac, Séverine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231186/
https://www.ncbi.nlm.nih.gov/pubmed/32260396
http://dx.doi.org/10.3390/mi11040382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231186/
https://www.ncbi.nlm.nih.gov/pubmed/32260396
http://dx.doi.org/10.3390/mi11040382

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